Company: Spectrum-Thea Pharmaceuticals Ltd.
Legal category: Prescription. Hospital. Sport permitted.
Active ingredient: Cefuroxime 50mg per vial.
Description: Powder for solution for injection.
Presentation: Vial-10, €100.37.
Indication: Prophylaxis of post-operative endophthalmitis after cataract surgery.
Pharmacology: Cefuroxime inhibits bacterial cell wall synthesis following attachment to penicillin binding proteins, which leads to bacterial cell lysis and death.
Dosage: Adult: Administer 0.1ml (1mg) by intracameral injection at the end of cataract surgery. Elderly: As per adults. Children: Not recommended.
Contraindications: Hypersensitivity to cefuroxime or to cephalosporins.
Special precautions: Caution: Prior allergic reaction to penicillins or any other beta-lactams. Consider alternative prophylactic antibiotic in patients at risk for infections with resistant strains. Only use after careful risk/benefit assessment: Patients with severe risk of infection, complicated cataracts, combined operations with cataract surgery, severe thyroid disease, or <2000 corneal endothelial cells. Monitor for corneal endothelial toxicity (potential risk).
Drug interactions: None known.
Adverse drug reactions: None common.
Full prescribing information and references available from Spectrum-Thea Pharmaceuticals Ltd. Telephone: +44 (8701) 923283.